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Anti -Caspase-12 Mouse mAb

货号:GB12548

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description

Caspase-12 Mouse Monoclonal 

Protein full name Caspase-12
 

Synonyms

Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene)

Immunogen

Recombinant protein corresponding to Mouse Caspase-12

Isotype IgG
Purity Affinity purification

Predicted MW.

48 kDa

Observed MW.

 kDa

Uniprot ID

O08736

 


 

Applications

 

Applications

WB

Species

Mouse

Dilution

1: 500-1: 1000

Positive tissue

testis

 


 

Background

 

Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.
 


 

Images

 

Western blot analysis of Caspase-12 (GB12548) at dilution of 1: 1000
Lane 1: NIH/3T3 cell lysate
Lane 2: L929 cell lysate
Lane 3: C2C12 cell lysate
Lane 4: Mouse heart tissue lysate
Lane 5: Mouse lung tissue lysate
Lane 6: Mouse muscle tissue lysate
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.