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Anti -VEGFA Rabbit pAb

货号:GB11034B

品牌:Servicebio

价格:¥650

规格: 100 μl

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Product Information

 

Description

VEGFA rabbit polyclonal

Protein full name Vascular endothelial growth factor A
 

Synonyms

VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse VEGFA 

Isotype IgG
Purity Affinity purification

Predicted MW.

34-45 kDa

Observed MW.

34-45 kDa

Uniprot ID

P15692Q00731P16612

 


 

Applications

 

Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 1000

Positive tissue

B16, liver cancer, kidney

 


 

Background

 

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .
 


 

Images

 

Western blot analysis of VEGFA (GB11034B) at dilution of 1: 1000.
Lane 1: B16 cell lysate
Lane 2: Human nasopharyngeal carcinoma tissue lysate
Lane 3: Human liver cancer tissue lysate
Lane 4: Human liver tissue lysate
Lane 5: Mouse kidney tissue lysate
Lane 6: Mouse brain tissue lysate
Lane 7: Rat kidney tissue lysate
Lane 8: Rat brain tissue lysate
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.